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BlogSaiba mais sobre o direito empresarial

23 de março de 201913

[vc_row][vc_column][ultimate_heading main_heading=”Saiba mais sobre o direito empresarial” main_heading_color=”#000000″ alignment=”left” spacer=”line_only” spacer_position=”bottom” line_height=”2″ line_color=”#b9684b” main_heading_font_family=”font_family:Lora|font_call:Lora|variant:regular” main_heading_style=”font-weight:normal;font-style:normal;” main_heading_font_size=”desktop:40px;” line_width=”60″ spacer_margin=”margin-top:10px;” margin_design_tab_text=””][/ultimate_heading][vc_column_text css=”.vc_custom_1553327526323{margin-top: 20px !important;}”]Atualmente as questões empresariais estão cada vez mais complicadas de se lidar. Os empresários têm de atender as demandas internas da empresa, se atentar ao ambiente externo a organização, a situação econômica do país e as diversas situações que aparecem no decorrer do desenvolvimento do negócio. Aliado a isso, muitas vezes, as empresas não possuem um setor jurídico próprio. Sendo assim, é necessário que a administração conte com um escritório de advocacia responsável e de confiança para resolver as questões jurídicas que um negócio demanda.

De Figueiredo Demeterco & Sade Sociedade de Advogados é um escritório focado nas demandas inerentes ao universo empresarial. Com respeito a nosso cliente, oferecemos sempre uma assessoria jurídica de qualidade, com uma equipe de advogados qualificada para ajudar os seus negócios a se desenvolverem de forma positiva no mercado atual.

Advocacia empresarial

É sabido que a graduação em Direito abre um amplo leque de alternativas para encaminhamento da carreira profissional. O direito empresarial é uma das áreas que vem ganhando muito destaque aos olhos dos recém-formados e também de profissionais que já atuam em outra esfera do direito, pois oferece uma grande diversidade de situações.

As questões jurídicas empresariais, basicamente, podem ser divididas em dois pontos de vista; o da empresa e o do funcionário. Sendo assim, é importante que quem for prestar a assessoria nesses casos tenha conhecimento jurídico em ambos os lados.

O uso do direito na área empresarial

Atualmente boa parte das empresas não possui um departamento jurídico de qualidade somente as grandes empresas que tem um grande número de funcionários investem em um departamento interno de advogados, outras empresas optam por terceirizar os problemas de jurídicos para um escritório de advocacia externo e de boa reputação, porém toda empresa necessita de uma assessoria jurídica seja ela empresa pequena, média ou de grande porte.

Dentre as necessidades que uma empresa tem quando precisa de uma advocacia empresarial podemos citar os mais variados motivos. Dentre os principais estão às obrigações trabalhistas, para contratação e demissão de funcionários, a advocacia tributária para a orientação de pagamentos de tributos e encargos em geral e por fim, a advocacia empresarial que tem como principal função garantir bom funcionamento da sua empresa com toda segurança jurídica que você possa necessitar.

Há tempos, uma das funções fundamentais de advogados que lidam em um ambiente empresarial é semelhante a de bombeiros: apagar incêndios. Já há algum tempo, porém, os advogados vêm progressivamente acumulando essa função com a de prevenção de incêndios. Muitos clientes corporativos já entendem valor dessa atividade. No entanto, para exercê-la com competência, os advogados precisam entender funcionamento e a cultura do mundo dos negócios — tanto quanto ou talvez mais do que entendem mundo jurídico.

É evidente a mudança no perfil da advocacia empresarial trabalhista nos últimos anos, tendo o advogado trabalhista sido extremamente valorizado, pois este passou a desempenhar papel de fundamental importância, não apenas na gestão do contencioso administrativo ou judicial, mas também e, principalmente, no suporte ao desenvolvimento e na gestão da estratégia econômico-financeira da organização empresarial, através da implementação efetiva da consultoria preventiva trabalhista e no suporte a gestão das pessoas.

Diante dessa nova realidade, a consultoria empresarial trabalhista passou a ser encarada como uma ferramenta extremamente útil e importante para sucesso das organizações empresariais, visto que, além de antever e poder prevenir situações de risco, atuando para evitar contencioso judicial, também auxilia e contribui em decisões importantes para a manutenção da saúde financeira da empresa e, consequentemente, colabora com sucesso do negócio.

Direito empresarial em Curitiba

Com soluções inovadoras e criativas a De Figueiredo Demeterco & Sade Sociedade de Advogados tem a tradição e envolvimento familiar com o direito a mais de 45 anos, isso garante a solidez e experiência de mercado que é necessário para a melhor solução das questões jurídicas de sua empresa. A busca pelo constante aprimoramento, assim como a excelência no serviço prestado leva o escritório a um patamar de referencia no mercado de assessoria jurídica para empresas.

Conheça um pouco mais sobre nosso trabalho, acesse: www.dfds.adv.br ou ligue para o telefone: (41) 3099-9899.[/vc_column_text][/vc_column][/vc_row]

13 comments

  • Marcelo

    23 de março de 2025 at 14:48

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    Nevertheless, it’s strongly advised to carry out 2-4 warm-up sets for your first carry of each session (and as wanted for the other primary lift), progressively growing to your working weight.
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    If you only do one exercise on your biceps, this traditional movement
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    I’ve spent the last three many years testing the effectiveness of hundreds of various workout routines.
    During this lifelong journey, I really have discovered what I imagine are the best workout routines for constructing robust, sculpted arms.

    One Other thing to point out is that the gradual enhance of energy
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    then you can start your bulking part. Whole day by day calorie expenditure is
    the quantity of calories your body consumes every day.
    If you eat at your TDEE, then you will simply keep your weight.
    As you turn out to be extra advanced, building muscle
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    It’s not unusual to pack on kilos and pounds of pure mass during a muscle bulk.
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    All The Time seek the guidance of with a
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    The content material on our web site is for informational and educational
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    References:

    why do anabolic steroids differ from other illegal drugs?; Marcelo,

  • https://git.fuwafuwa.moe/henvirgo8

    11 de abril de 2025 at 07:04

    The dose you get for a cycle on Trenbolone largely
    is dependent upon which sort you opt for and how experienced you would possibly be as a
    user. If you’re new to this steroid, it’s typically recommended you go together with TA as
    it’s quicker performing and clears from your blood a lot faster than TE.
    These primarily rely upon the dose, with higher doses of
    androgen coming with a higher likelihood of unwanted effects.

    We have found trenbolone to be some of the doubtless steroids to cause hair
    loss, recession, or thinning on the scalp because of its highly androgenic nature.
    When determining Ment’s suitability as a prescription medication for male contraception or HRT, its effect on the prostate
    is of critical significance. This make or break factor was evaluated proper from the start, with promising results.

    Post-cycle remedy (PCT) is a crucial consideration when planning Trenbolone administration. Due to its strong suppressive effects on pure
    hormone production, a sturdy PCT protocol is critical to assist restore the physique’s natural
    hormone stability after a cycle. This typically includes the
    use of compounds like Clomid or Nolvadex, often starting
    a couple of weeks after the last Trenbolone injection,
    depending on the ester used.
    Buying these medication illegally poses vital risks, including authorized consequences and
    the potential for counterfeit or contaminated merchandise.

    When utilizing a Take A Look At and Tren cycle, understanding the
    distinction between bulking and cutting cycles is important.
    Each Test (testosterone) and Tren (trenbolone) may help with constructing muscle and shedding fats, however the targets and methods for each cycle
    range. For some customers, this suppression of natural testosterone production may turn into long-term and even everlasting, requiring
    lifelong hormone therapy. Trenbolone is especially highly effective and can disrupt hormone levels
    even more severely than testosterone. It also can result in gynecomastia (development of breast
    tissue in men) if estrogen levels increase in response to
    the steroid use. Test and Tren customers often attempt to manage hormonal imbalances by incorporating
    different drugs, like aromatase inhibitors, to scale back estrogen ranges.

    Nonetheless, when abused, the rise in red blood cells may cause blood
    clots, which may require you to seek medical attention. In some circumstances, Masteron can act as a direct type of testosterone within the body, which suggests
    that you can count on similar outcomes when taking Testosterone.
    However, this will happen provided that the extent of DHT in your physique is too low,
    something that doesn’t occur very often nowadays.
    Oxygen plays a significant position in energy production, so the red cells are also
    essential for muscle growth. When we head to the health club and workout, the
    primary purpose is to encourage muscle growth.
    Contemplate integrating Trenbolone Cycle Stacking for enhanced efficiency and features.

    By combining Trenbolone Acetate with different performance enhancers, you’ll be able to take your
    outcomes to the subsequent degree.
    Unfortunately, it also increases the body’s ranges of dihydrotestosterone (DHT), an androgen that encourages the shedding
    of hair follicles inflicting male sample baldness and receding hairlines.

    As such, it is very important use caution when using this drug and by no means
    exceed the beneficial dosage levels, which may range
    from one hundred fifty mg to 400 mg weekly relying on the user’s tolerance ranges.
    It is essential to adjust the dosage to go nicely with particular person needs whereas noting potential unwanted side effects similar
    to unexpected weight acquire or temper swings that might arise from using an extreme amount of
    of the drug at once. Nonetheless, stacking with other types of steroids may help more experienced customers get the most out of their cycles whereas minimizing the side
    effects that include long-term use. Trenbolone is a powerful androgenic steroid, mostly
    found within the forms of enanthate, acetate, and hexahydrobenzylcarbonate
    (Tren-Hex or Parabolan). Trenbolone, also referred
    to as Tren, is an androgenic-anabolic steroid that has a very excessive ratio
    of anabolic to androgenic effects. This potent steroid brings plenty of
    benefits to athletes, bodybuilders, and weightlifters who wish to be in top kind during the competitors.

    This could be helpful for bodybuilders who want to find a
    way to modify their dosage shortly in the occasion that
    they expertise side effects. Nevertheless, it is very important note that
    Trenbolone acetate can come with some unwanted effects, as mentioned above.
    Some customers can also experience irritability and gynecomastia (enlarged breast
    tissue in men). These unwanted aspect effects are sometimes dose-dependent,
    which means they turn into more likely because the
    dosage will increase. Trenbolone could cause a variety of
    adverse effects, including zits, hair loss, and temper swings.

    This is a steroid with several advantages and some disadvantages you’d be conversant in. No Matter
    you choose to stack Trenbolone with, together with Testosterone
    as a base, is obligatory to keep away from complete
    sexual dysfunction. Bulking, recomp, slicing, strength
    – Trenbolone is so versatile that you’ll use it in nearly any stack.

    One of the main benefits of Trenbolone Acetate is its
    capability to promote muscle growth and enhance energy.
    It Is often compared to different steroids, such
    as Deca Durabolin and Dianabol, which are also identified for his or her muscle-building properties.

    However, many bodybuilders prefer Trenbolone Acetate because it tends to produce much less water retention than these other steroids, which might lead to a more outlined and lean appearance.
    Trenbolone acetate is a popular ester pro-drug of trenbolone, a synthetic anabolic
    steroid that’s estimated to be three to five instances more potent than testosterone on the androgen receptor [1].
    It Is necessary to acknowledge that there are alternatives to Trenbolone,
    both throughout the realm of anabolic steroids and beyond.

    All comparisons are made in relation to testosterone, which is the baseline and has an androgenic and anabolic score of 100.
    The Hershberger Assay technique was the first formal method
    of quantifying steroid power in each these areas.

    Moreover, Tren Ace can help in fat loss by rising
    your metabolic rate and promoting the breakdown of saved fats
    for power.

    References:

    best place to inject steroids (https://git.fuwafuwa.moe/henvirgo8)

  • Winstrol Steroid Before And After

    12 de abril de 2025 at 21:04

    However Winstrol can promote a shocking amount of lean gains,
    which come without water weight. Winstrol can also be utilized in veterinary drugs to extend urge for
    food and red blood cell manufacturing and help with weight acquire.
    In the world of horse racing, Winstrol turned a sought-after unlawful performance-enhancement drug.

    Anavar cycle might help improve general energy and efficiency, while additionally
    preventing accidents and aiding in weight loss. Monitoring your well being
    with an Anavar cycle is crucial to make sure that you are getting probably the most out of this
    powerful drug. Though Anavar may be a less toxic compound compared to different
    anabolic steroids, its advantages are not without danger.
    Nevertheless, such stacking will enhance the chance of masculinization while exacerbating cholesterol and endogenous testosterone levels.
    Anavar is usually considered “female-friendly” by our patients when taking 5–10 mg per day for 5–6 weeks.

    The Meals and Drug Administration (FDA) granted orphan drug status for the remedy of alcoholic hepatitis, Turner syndrome,
    and HIV-induced weight reduction in subsequent years. It can additionally be indicated as an antidote to catabolism introduced
    on by extended corticosteroid therapy. When it comes to choosing the most
    effective steroid for operating, there are several choices listed
    in various sources. Different steroids that have been instructed embody Clenbutrol, Trenorol, and Winsol.

    Anavar is a 17-alpha alkylated oral steroid, which means it’s been modified to survive the first
    cross through the liver.
    Nonetheless, with Anavar’s fat-burning results and muscle positive aspects being retained post-cycle,
    there is not an excellent want for most people to make the most of Anavar all yr
    spherical. We find Anavar peaks fast within the bloodstream due to its quick half-life of 9–10
    hours. In our experience, customers commonly notice an improvement in body composition within the first two weeks.

    Nonetheless, they don’t include any of the health or authorized
    dangers, both. Anavar could cause people to burn extra
    fat and construct lean muscle, rising energy. The anabolic effects
    of this steroid are stronger than its androgenic effects.

    If your response is constructive and you may be feeling a slight dose increase is necessary, you probably can bump
    it as much as 15 mg, the maximum dose for any woman shouldn’t exceed 20mg per day.
    Women who take a brief cycle of Anavar often do not expertise unwanted aspect effects, nonetheless,
    since everyone appears to be physiologically different side
    effects will vary. How quick Winstrol works, inflicting peak serum testosterone levels,
    will depend on the method of administration. Nevertheless, oral Winstrol is more handy, as our
    sufferers generally report Winstrol injections as painful.
    Subsequently, with injectable Winstrol, users are successfully taking a better dosage as a result of its larger biological availability.
    Thus, oral Winstrol is extra easily damaged down and cleared by the physique; thus, extra regular dosing is required to take care of
    peak serum testosterone.
    Only tablets can be found for purchase, and so they have to be swallowed entire.
    Anavar can improve sports activities efficiency without critical risks, making it appealing
    to athletes. The similar brand of Anazol also is obtainable in oral kind in 2mg tablets, which can be interesting if you’re taking decrease doses of
    Stanozolol.
    Experimenting with totally different dosing schedules is always the easiest way to find what works best for you.
    Anavar may also trigger masculinization in girls; nevertheless, we don’t sometimes observe this in therapeutic doses.
    However, excessive dosages or combining Anavar with different anabolic steroids similar to Winstrol
    increases the probability of masculinization. A user’s outcomes on Anavar will depend upon their cycle, dose, genetics,
    food regimen, and coaching routines.
    Anavar would have to be one of many two most well-known oral steroids –
    the other being the well-known Dianabol. When we examine Anavar to other
    steroids, it’s thought of mild, but in actuality, it could
    possibly still have substantial effects (both optimistic and negative)
    at greater doses (more on that below). In addition,
    Anavar also can enhance blood pressure and levels of cholesterol,
    each of that are danger components for coronary heart illness.
    As a end result, people who take Anavar could additionally
    be at an elevated danger of growing coronary heart illness.

    In addition, Anavar helps to extend protein synthesis,
    which is the process that helps muscular tissues to grow larger and
    stronger. Alcohol has a negative impact on cortisol ranges (35); thus, fat-burning
    may turn out to be inhibited. Moreover, cortisol is a catabolic hormone, that means heavy alcohol consumption may scale back muscle mass.

    In addition, we will present guidance on how to use this steroid safely and keep away from any
    potential unwanted effects. Maintain in mind that a maximum female
    dosage of 20mg is considered absolutely the limit earlier than your chances of growing
    virilizing unwanted facet effects enhance substantially.
    It’s nearly ensured that virilization will occur
    at dosages above 20mg. In the occasion that girls use Anavar
    for longer than a 6-week cycle, the probabilities virilizing
    secondary effects creating increments substantially. Though a Winstrol-only cycle isn’t a common selection for male customers,
    PCT is still required when you do go this route. A quality part of Clomid PCT following a Winstrol
    cycle is, due to this fact, important.
    This means no aromatizing and no estrogenic results like water
    retention. Primo can additionally be considered a comparatively gentle steroid with less androgenic efficiency and fewer virilization threat than Winstrol.
    A most dosage of 100mg/day is usually thought-about by
    advanced customers of Winstrol, significantly for an upcoming competitors.
    In this case, a complicated Winstrol cycle may involve utilizing 50mg/day for four
    weeks, growing to 100mg/day for the ultimate two weeks of this 6 to 8-week
    cycle.

    References:

    Winstrol Steroid Before And After

  • anabolic steroid results

    25 de abril de 2025 at 17:45

    Son fármacos antiinflamatorios e inmunosupresores, de acción bastante rápida, e indicados fundamentalmente
    en procesos agudos. La trembolona es un esteroide anabólico ampliamente conocido
    por sus propiedades potentes, que han atraído la atención de muchos atletas y
    culturistas en busca de un rendimiento mejorado.
    Antes de utilizar trembolona u cualquier otro esteroide
    anabólico, es essential buscar el asesoramiento de un profesional de la salud, como un médico o un especialista en medicina deportiva.
    Es fundamental tener en cuenta que el uso de este compuesto debe ser supervisado por profesionales de la
    salud, ya que el abuso o mal uso de este esteroide puede tener
    consecuencias graves para la salud a corto y largo plazo. Además, la trembolona también puede mejorar la eficiencia en la utilización de nutrientes, lo que significa que el cuerpo puede aprovechar mejor los
    nutrientes para el crecimiento muscular y la recuperación. Para el atleta masculino fuera de
    temporada, esto no será lo que consideraríamos un esteroide
    voluminoso principal; de hecho lo llamaríamos débil para este
    propósito. Pero su poder anabólico se traducirá tremendamente en un ciclo de
    corte, o con el propósito de mejorar el atletismo directo.

    Esto debería incluir una dieta amistosa con colesterol rica
    en ácidos grasos omega, así como también mucha actividad
    cardiovascular. Este esteroide aumentará la fuerza; el aumento complete no será tan significativo como los esteroides como Dianabol
    pero será notable. La fuerza es uno de los principales
    factores del atletismo exitoso, ya que se traduce en velocidad y poder.
    La clave para una dieta exitosa es perder la grasa deseada mientras se mantiene la mayor
    cantidad de tejido magro posible. No importa cuán bien planificada sea su dieta,
    se producirá cierta pérdida muscular si no se encuentra
    un poderoso agente anabólico.
    Y es que, aunque los esteroides anabólicos están prohibidos en el mundo del
    deporte, son muchas las personas que los consumen. El tiempo que tardan en hacer
    efecto los anabolizantes puede variar según varios factores,
    como el tipo de anabolizante utilizado, la dosis y la frecuencia de administración, así como las características individuales de cada persona.
    En algunos casos, se pueden observar resultados en cuestión de semanas, mientras que en otros puede llevar más tiempo.
    Los servicios de emergencia y de derivación profesional que
    se listan arriba están disponibles para las personas que se
    encuentran en Estados Unidos. Tales servicios no son operados por el Instituto Nacional sobre
    el Abuso de Drogas (NIDA).
    Por el contrario, Rotmensch et al27 evidenciaron en un estudio prospectivo y
    aleatorizado de recién nacidos prematuros expuestos a dexametasona o betametasona una clara supresión transitoria de la actividad biofísica cardíaca y del ritmo cardíaco.
    Hallazgos similares se objetivaron en otros dos estudios prospectivos aleatorizados en los que se analizó la variabilidad del ritmo cardíaco fetal
    en fetos nacidos prematuramente bien con un crecimiento normal28 o en los que presentaban retardo
    de crecimiento29. En la década de 1930, ya se sabía que
    los testículos contienen un andrógeno más poderoso que la androstenona, y
    tres grupos de científicos, financiados por compañías farmacéuticas competidoras en los Países Bajos, Alemania y Suiza,
    se apresuraron a aislarlo. Esta hormona fue identificada por primera vez por Karoly Gyula David,
    E. Dingemanse, J. Freud y Ernst Laqueur en un artículo de
    mayo de 1935 “Sobre la hormona masculina cristalina de los testículos (testosterona)”.
    Llamaron a la hormona testosterona, de las raíces de testículo
    y esterol, y el sufijo de cetona. La síntesis química de la testosterona se logró en agosto
    de ese año, cuando Butenandt y G.
    El óxido nítrico es el mediador de la relajación del músculo liso trabecular y arterial intracavernoso.
    En animales castrados, la administración de testosterona
    o DHT restableció la función eréctil y la expresión de NOS en el cuerpo cavernoso34,35.
    También se ha demostrado que la testosterona regula la actividad de
    la fosfodiesterasa 5 (PDE5).
    Sin embargo, en las investigaciones no se demuestra con claridad
    que la hormona humana del crecimiento estimule la fuerza o ayude a las personas a hacer ejercicio durante más tiempo.

    Los adolescentes que toman esteroides anabólicos pueden crecer menos de lo ordinary
    y correr mayor riesgo de tener problemas de salud en el futuro.
    Infórmate más sobre los efectos en la salud de las sustancias para mejorar el rendimiento.
    En resumen, el consumo de anabolizantes, lejos de ser un problema baladí,
    en muchos países supone un problema de salud pública.
    Como profesionales de la salud, es nuestra obligación estar alerta ante el uso
    de estas sustancias e informar a los pacientes y divulgar a la sociedad, en general, los riesgos que entrañan para la salud.
    Acondicionamiento corporal mejorado, aumento
    demasa muscular, incremento de fuerza y quema de grasa.
    Las rupturas de tendones en levantadores de pesas han sido asociadas con el consumo de esteroides,
    aunque no existe evidencia alguna que sugiera que la incidencia es mayor en consumidores de esteroides anabólicos en comparación con deportistas que no
    los utilizan. Es probable que todo tendón desgarrado que pueda presentarse sea el resultado de la incapacidad
    del tendón para compensar el rápido incremento de masa muscular y capacidad generadora de fuerza que se presentan durante un ciclo de
    altas dosis de esteroides anabólicos. Los efectos secundarios más comunes de los
    corticosteroides incluyen aumento de peso, retención de líquidos, alteraciones
    en el metabolismo, debilitamiento óseo y supresión del sistema inmunológico.
    Además, es basic informar al paciente sobre los posibles efectos secundarios y las medidas
    para controlarlos. Mejoras en la fuerza en el rango de 5 a 20% de la fuerza inicial,
    dependiendo en gran medida de los medicamentos
    y la dosis utilizada, así como del período de administración.
    Los esteroides anabólicos son variaciones sintéticas, es decir, creadas
    por el hombre, de la hormona sexual masculina testosterona.

    Anabólico se refiere al desarrollo muscular, y androgénico al aumento de las características sexuales masculinas.
    La metiltestosterona, 200 mg/sem, no produce efectos adversos (incluso ni en la personalidad), exceptuando un ligero aumento
    del acné. La mayoría de los efectos adversos ocurren con dosis superiores a 200 mg semanales de metiltestosterona.
    Los efectos de los tratamientos a largo plazo no han sido estudiados, ni tampoco los efectos de dosis extraordinariamente altas que usan algunos atletas, en especial los culturistas, que algunas veces utilizan dosis
    equivalentes a varios gramos semanales de metiltestosterona.

    Como la DHT es de three a 10 veces más potente como agonista del AR que la
    testosterona, la actividad agonista del AR de la testosterona se potencia marcada y selectivamente en dichos tejidos.
    Además, algunos derivados de la 19-nortestosterona,
    incluida la trestolona (7α-metil-19-nortestosterona (MENT)), 11β-metil-19-nortestosterona (11β-MNT) y dimetandrolona (7α,11β-dimetil-19-nortestosterona), no puede reducirse
    en 5α. Por el contrario, ciertos AAS alquilados en 17α como la metiltestosterona se reducen en 5α y se potencian en tejidos androgénicos
    de manera similar a la testosterona.Sin embargo, los derivados de DHT 17α-alquilados no se pueden potenciar a través de la 5α-reductasa,
    ya que ya están reducidos en four,5α. Se ha descubierto
    que algunos AAS, como la testosterona, la DHT,
    el estanozolol y la metiltestosterona, modulan el receptor GABA A de manera comparable a los
    neuroesteroides endógenos como la alopregnanolona, ​​el 3α-androstanediol, el sulfato de
    dehidroepiandrosterona y el sulfato de pregnenolona.

    La combinación de suficiente activación de AR y PR
    puede suprimir los niveles de testosterona circulante en el rango de
    castración en los hombres (es decir, la supresión completa
    de la producción de testosterona gonadal y los
    niveles de testosterona circulante disminuyeron en aproximadamente un 95%).
    Como tal, la actividad progestágena combinada puede servir para
    aumentar aún más la relación miotrófica-androgénica para un AAS dado.
    Además, la DHT es inactivada por la alta actividad de 3α-HSD
    en el músculo esquelético (y el tejido cardíaco), y de manera related, se podría
    esperar que los AAS que carecen de afinidad por 3α-HSD tengan una
    relación miotrófica-androgénica más alta
    (aunque quizás también un aumento de largo plazo).

    La acción de la aldosterona se ejerce fundamentalmente a nivel de la porción last del tubo distal y en los conductos colectores, en donde la
    hormona promueve la reabsorción de Na+ y la secreción de K+.
    Estas hormonas difunden a las células granulosas vecinas, las cuales poseen la enzima aromatasa que las convierte en estrona (E1)
    y 17β-estradiol (E2). El folículo maduro posee unas células en su teca
    que producen andrógenos como la androstenediona y la testosterona.
    El mineralocorticoide más importante es la aldosterona sintetizada en la zona glomerular de la corteza suprarrenal, pero los glucocorticoides despliegan también actividad mineralocorticoide.
    En cuanto a la sangre, el cortisol favorece el proceso de coagulación, estimula la formación de granulocitos
    neutrófilos e inhibe la de eosinófilos, basófilos, monocitos y linfocitos
    T.

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